Retrophin is now enrolling patients in the PROTECT Study, a global Phase 3 clinical research study, to determine whether sparsentan can reduce the amount of protein in the urine and slow down the decline of kidney function in patients with IgAN.
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Kiryluk K, Li Y, Sanna-Cherchi S, Rohanizadegan M, Suzuki H, et al. (2012) Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis. PLoS Genet 8(6): e1002765. doi:10.1371/journal.pgen.1002765