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HOW IS IGA NEPHROPATHY TREATED?

There is no current cure for IgAN and that is why the IgA Nephropathy Foundation of America was founded. Since the disease varies from one person to another, there is no definite progression or course that the disease will take. What works for one person may have virtually no effect on another, but our goal is to bring those with IgAN together to share experiences and bring awareness to this disease.

Since there is no cure, treatments focus on slowing the progression of the disease and preventing complications. Some individuals experience complete remission, while others live normal lives with medications to treat their symptoms (such as high blood pressure meds, immunosuppressants, omega 3 fatty acids & vitamin E supplements), yet others experience complete kidney failure (end-stage kidney disease) and require either dialysis or a kidney transplant depending on the severity. It is estimated that as many as half of those affected with IgAN will develop end-stage renal disease. This poses one large problem… there aren’t enough kidneys and many patients wait on the transplant list for years.

References

  • Hall, Y.N., Fuentes, E.F., Chertow, G.M. et al. Race/ethnicity and disease severity in IgA nephropathy. BMC Nephrol 5, 10 (2004). https://doi.org/10.1186/1471-2369-5-10
  • Kiryluk K, Li Y, Sanna-Cherchi S, Rohanizadegan M, Suzuki H, et al. (2012) Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis. PLoS Genet 8(6): e1002765. doi:10.1371/journal.pgen.1002765