John Marsala was diagnosed with IgA Nephropathy in 2005. He lives in Westbury, NY with his wife Maureen, who donated a kidney to him in January of 2022. He became an area representative for the IgA Nephropathy Foundation in March 2014 and was asked to sit on the Executive Board in November that year. In his time at the Foundation so far, he has organized fundraising events, represented the Foundation on Capitol Hill to request research funding, discussed IgAN with FDA members to streamline drug approvals, and attended meetings with the American Society of Nephrology and National Institute of Diabetes and Digestive and Kidney Diseases to discuss upcoming events and research plans. In 2020, he shared his story in an IgA Nephropathy feature on the Lifetime Channel.